Probiotics reduce allergic response in infants
(NaturalNews) Early exposure to probiotics may reduce a child's lifetime
allergy risk, according to a recent study conducted by Swedish
researchers and published in the journal
Clinical and Experimental Allergy.
The
researchers collected blood from 61 children at the time of birth, as
well as at six, 12 and 24 months of age. At every age tested,
supplementation with probiotics (
Lactobacillus reuteri) was associated with healthier immune responses and lower levels of immune response to allergens.
"
L. reuteri supplementation from week 36 and during the first year of life
significantly decreases IgE-associated eczema and lowers allergen and
mitogen responsiveness," the researchers concluded.
Probiotics
are microorganisms that perform beneficial functions in the body,
particularly in the regulation of the digestive and immune systems. Some
researchers have speculated that lack of exposure to such beneficial
bacteria (and even lack of exposure to certain harmful bacteria) may
prevent children's immune systems from developing properly. This is
known as the "hygiene hypothesis."
For this reason, many
researchers have suggested that early supplementation with probiotics
might help mimic a more natural human environment and thereby lead
children to have healthier immune systems and lower rates of immune
dysfunctions such as allergies.
"[Probiotics] are probably
closely mimicking the effects of regularly eating unpasteurized and
unsterilized food," said pediatric immunologist and probiotics
researcher Anthony Horner, of the
University of California-San Diego.
The immune system needs bacteriaThe
new study is not the first to show a connection between probiotics and
lower allergy rates. Earlier research has shown, for example, that
infants who suffer from allergies are more likely to have abnormal
compositions of intestinal microbes, including higher levels of
clostridia and lower levels of bifidobacteria.
Other studies have shown that
infants suffering from atopic eczema, a common childhood allergy, experienced significant symptom improvement when supplemented with
Lactobacillus rhamnosus GG or
Bifidobacterium lactis Bb-12. In a study published in the
Journal of Nutrition in 2007, researchers found that infants who were deliberately exposed to non-pathogenic
E. coli suffered from significantly fewer allergies at ages 10 and 20.
A preventive treatmentIt
may even be possible to inoculate children against allergies by
exposing them to probiotics in utero, while their mothers are still
pregnant, according to a study conducted by researchers from the
University of Helsinki, Finland, and published in the journal
Clinical and Experimental Allergy in 2008.
The
researchers assigned 1,223 women to take a daily dose of either a
probiotic or a placebo starting in the eighth month of pregnancy. All
participants or their partners had a history of
allergies,
thereby classifying their children as "predisposed" to developing
allergies. Starting at birth and for the first six months of life, 925
infants were also assigned to take the same probiotic or placebo dose
that their mothers had received during pregnancy.
The researchers
examined the children for allergies at three, six and 24 months of age.
They found that among children who had been treated with
probiotics,
levels of inflammation-related chemicals were 50 percent higher,
indicating a healthier immune response and a lower risk of allergies. In
addition, children who had taken probiotics were 30 percent less likely
to develop atopic eczema than children who had been treated with the
placebo.
"It seems clear that we need to stimulate the infant's
immune system as early and as vigorously as is safe, for inflammation
seems to go hand in hand with allergy prevention," study author Errki
Savilahti said.
"Even if someone has the genes for allergies,
these results suggest that people can take action to at least reduce the
chances of developing early allergic conditions like eczema," allergist
Richard Katz said.
source:-
http://www.naturalnews.com/039934_probiotics_infants_allergies.html